Halade team, at USF identifies mouse model to better study prevalent form of heart failure linked to age-related obesity. The study shows that female mice can better survive heart failure after heart attack, have more reparative immune cells and higher levels of signaling molecules with anti-inflammatory effects than males.
The study published in ESC Heart Failure delineates a potential avenue to safely resolve acute inflammation after heart attack-induced tissue injury, with the aim of finding more individualized therapies for heart failure.
The article published by Halade team in FASEB journal on the impact of high-fat diet on aging mice (2019) comes in the top 5% of all research outputs (scored by Altmetric). The study implied that older adults consuming high-fat diet at risk of heart disease and diabetes as cited in Yahoo Finance and many other medical journals.
Halde lab has proven in their study that in cardiac injury, the nonsteroidal anti-inflammatory drugs carprofen causes dysfunction of the immune system.
The outcome of our teamwork published in American Journal of Physiology in November 2018 showed that commonly used chemotherapy drug can lead to heart failure study. This work is well recognized by Yahoo News, and many other media.